Detalhe da pesquisa
1.
Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial.
Lancet;
401(10373): 281-293, 2023 01 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36566761
2.
Therapeutic Clearance of Amyloid by Antibodies to Serum Amyloid P Component.
N Engl J Med;
373(12): 1106-14, 2015 Sep 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26176329
3.
A randomized, double-blind, placebo-controlled trial of camicinal in Parkinson's disease.
Mov Disord;
33(2): 329-332, 2018 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29278279
4.
The effect of camicinal (GSK962040), a motilin agonist, on gastric emptying and glucose absorption in feed-intolerant critically ill patients: a randomized, blinded, placebo-controlled, clinical trial.
Crit Care;
20(1): 232, 2016 08 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27476581
5.
Current usage of explainer animations in trials: a survey of the UKCRC registered clinical trial units in the UK.
Trials;
25(1): 224, 2024 Mar 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38549126
6.
Use of oxygen-loaded nanobubbles to improve tissue oxygenation: Bone-relevant mechanisms of action and effects on osteoclast differentiation.
Biomaterials;
305: 122448, 2024 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38218121
7.
Cost-utility analysis of molnupiravir plus usual care versus usual care alone as early treatment for community-based adults with COVID-19 and increased risk of adverse outcomes in the UK PANORAMIC trial.
Br J Gen Pract;
2024 Jan 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38228357
8.
Randomized controlled trial of molnupiravir SARS-CoV-2 viral and antibody response in at-risk adult outpatients.
Nat Commun;
15(1): 1652, 2024 Feb 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38396069
9.
Effect of ketoconazole on the pharmacokinetic profile of ambrisentan.
J Clin Pharmacol;
49(6): 719-24, 2009 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19389876
10.
Repeat doses of antibody to serum amyloid P component clear amyloid deposits in patients with systemic amyloidosis.
Sci Transl Med;
10(422)2018 01 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29298867
11.
Opioid Antagonists and the A118G Polymorphism in the µ-Opioid Receptor Gene: Effects of GSK1521498 and Naltrexone in Healthy Drinkers Stratified by OPRM1 Genotype.
Neuropsychopharmacology;
43(4): 927, 2018 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29422496
12.
The pharmacodynamics, safety and pharmacokinetics of single doses of the motilin agonist, camicinal, in type 1 diabetes mellitus with slow gastric emptying.
Br J Pharmacol;
173(11): 1768-77, 2016 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26924243
13.
Opioid Antagonists and the A118G Polymorphism in the µ-Opioid Receptor Gene: Effects of GSK1521498 and Naltrexone in Healthy Drinkers Stratified by OPRM1 Genotype.
Neuropsychopharmacology;
41(11): 2647-57, 2016 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27109624
14.
The effects of alcohol on the pharmacokinetics and pharmacodynamics of the selective mu-opioid receptor antagonist GSK1521498 in healthy subjects.
J Clin Pharmacol;
53(10): 1078-90, 2013 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23934621
15.
Multiple-dose safety, pharmacokinetics, and pharmacodynamics of the µ-opioid receptor inverse agonist GSK1521498.
J Clin Pharmacol;
52(10): 1456-67, 2012 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22162534
16.
Effects of mu opioid receptor antagonism on cognition in obese binge-eating individuals.
Psychopharmacology (Berl);
224(4): 501-9, 2012 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22752384
17.
Opioid receptor modulation of hedonic taste preference and food intake: a single-dose safety, pharmacokinetic, and pharmacodynamic investigation with GSK1521498, a novel µ-opioid receptor inverse agonist.
J Clin Pharmacol;
52(4): 464-74, 2012 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21610207
18.
Treatment with a peroxisomal proliferator activated receptor gamma agonist has a modest effect in the allergen challenge model in asthma: a randomised controlled trial.
Respir Med;
104(5): 668-74, 2010 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19944580
19.
Effects of multiple doses of ambrisentan on the pharmacokinetics of a single dose of digoxin in healthy volunteers.
J Clin Pharmacol;
51(1): 102-6, 2011 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20350954